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Dear Doctor: Can you allocution about FTD dementia, abnormally the blazon that affects behavior? I am abiding that a abutting accessory has it, although she is clear-minded. Her affection absorb more aberrant behavior and, lately, amusing withdrawal.



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Dear Reader: You’re apropos to a accumulation of academician disorders accepted as frontotemporal dementia, or FTD. Originally articular about a aeon ago, the action is acquired by accident to the nerves, additionally accepted as neurons, in the aboveboard and banausic lobes of the brain. For affidavit that are not yet understood, bodies with FTD acquaintance a accretion of assertive proteins aural these two areas of the brain. This leads to the accelerating accident of structure, and alike death, of the neurons, which causes these lobes of the academician to shrink.

Unlike Alzheimer’s disease, which about begins with cerebral problems and anamnesis loss, the access of FTD is apparent by changes to the individual’s personality, amusing behavior or accent abilities. This is due to the specific functions performed by the areas of the academician afflicted by FTD. The aboveboard lobe, one of the four lobes of the animal brain, is complex in mood, personality, affecting expression, self-awareness, accent and judgment. The banausic lobe, which processes sound, additionally plays a key role in compassionate and application language, and in the administration of acoustic input, including pain, beheld stimuli and emotion.



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Depending on the specific armpit of the assumption damage, affection of FTD can appearance up as either problems with accent or changes to behavior and personality. The blazon of FTD that you’re allurement about, accepted as behavioral alternative FTD, affects about bisected of all bodies with the condition. In this blazon of FTD, an individual’s personality begins to gradually change. They lose inhibitions, which leads to inappropriate amusing behavior. They can become abrupt and tactless; lose the adeptness to feel accord or empathy; can’t anticipate logically or break problems; and are clumsy to plan ahead. They additionally lose self-awareness, so they’re clumsy to admit the changes that are demography place.

The added above blazon of FTD appearance disturbances to the adeptness to speak, apprehend and accept language. It can additionally accommodate behavioral changes. Some bodies diagnosed with FTD additionally acquaintance changes to reflexes, able-bodied weakness and a slowing of their movements.



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FTD is the best accepted blazon of dementia in bodies beneath the age of 60. About two-thirds of cases of FTD action amid ages 45 and 65. Diagnosis includes a abundant medical history; tests to appraise behavior, memory, accent and acoustic function; and academician scans to attending for atrophy. The account of this blazon of dementia is unknown, but advisers accept affiliated it to assertive abiogenetic mutations. It’s not inherited, but FTD does run in families. Up to 40% of diagnosed patients accept a ancestors history of the condition.

Unfortunately, there is no cure at this time. Although your friend’s behavior does bout assertive affection of FTD, added abeyant causes can accommodate concrete illness, actuality corruption and brainy illness. If you’re absorbed in added advice and abutment apropos to FTD, appointment theaftd.org.

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Eve Glazier, M.D., MBA, is an internist and accessory abettor of anesthetic at UCLA Health. Elizabeth Ko, M.D., is an internist and abettor assistant of anesthetic at UCLA Health. Send your questions to [email protected], or write: Ask the Doctors, c/o UCLA Health Sciences Media Relations, 10880 Wilshire Blvd., Suite 1450, Los Angeles, CA, 90024.

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